The route connects US 82/SR 39/SR 50 in Georgetown with US 17/SR 25 in Brunswick, via Lumpkin, Preston, Americus, Vienna, Hawkinsville, Eastman, Helena–McRae, Hazlehurst, Baxley, and Jesup.
Then, the two highways diverge with SR 27 continuing through rural areas of the northeastern part of the county.
They curve to the southeast and enter Preston, where SR 41 briefly joins the concurrency.
Just before entering town, first SR 49 (Salters Mill Road), and then US 19/SR 3 (South Martin Luther King Boulevard), join the concurrency.
At this intersection, US 280/SR 27/SR 30 east/SR 49 turn to the right, while US 19/SR 3/SR 30 west (North Martin Luther King Boulevard) continue to the northeast.
Just past Oak Grove Cemetery, SR 49 departs the concurrency on Tripp Street.
It passes George Busbee Park and meets the western terminus of SR 215 (East Union Street).
[1] There are two portions of SR 27 that are part of the National Highway System, a system of routes determined to be the most important for the nation's economy, mobility, and defense: SR 27 was established at least as early as 1919 from Hawkinsville to a point northwest of Brunswick.
It was also designated south-southwest and curved to the southeast to end at SR 40 northwest of St. Marys.
Nearly the entire Dooly County portion of the Americus–Vienna segment of SR 28 had a "sand clay or top soil" surface.
East of Lumpkin and in the Preston area, SR 28 had a sand clay or top soil surface.
[7][8] By the end of the year, a portion of US 341/SR 27 east-southeast of Baxley had a sand clay or top soil surface.
Two segments of those highways were under construction: from Eastman to northwest of McRae and a portion east-southeast of Hazlehurst.
[18][19] By the beginning of October, the entire Wayne County portion of the Baxley–Jesup segment had a completed hard surface.
[19][20] By the end of the year, from Baxley to a point southeast of Jesup, US 341/SR 27 had a completed hard surface.
[23][24] In the first quarter of 1937, a portion of SR 28 in the southwestern part of Hawkinsville had a completed hard surface.
[32][33] In the third quarter of the year, the western half of the Quitman County portion of the Georgetown–Lumpkin segment was under construction.
The western half of the Quitman County portion of the Georgetown–Lumpkin segment had completed grading, but was not surfaced.
Also, the eastern part of the Sumter County portion of the Americus–Vienna segment had a sand clay or top soil surface.
[40][41] Between August 1950 and January 1952, the eastern half of the Dooly County portion of the Americus–Vienna segment was hard surfaced.
[42][43] In 1953, the entire Dooly County portion (except the extreme western part) was hard surfaced.
[50][51] In 1989, a southwestern bypass of Eastman, designated as SR 841, was proposed from US 341/SR 27 west of the city to US 23/US 341/SR 27 southeast of it.
[52][53] In 1993, US 341/SR 27 through Eastman was shifted southward out of the main part of the city onto the path of SR 841.
is a 3.9-mile-long (6.3 km) business route of SR 27 that exists entirely within the central part of Dodge County.
It begins just west of Eastman, at an intersection with US 341/SR 27.It travels to the northeast on Fish Road, concurrent with US 341 Bus./SR 46.
[3] In 1989, a southwestern bypass of Eastman, designated as SR 841, was proposed from US 341/SR 27 west of the city to US 23/US 341/SR 27 southeast of it.
[52][53] In 1993, US 341/SR 27 through Eastman was shifted southward out of the main part of the city onto the path of SR 841.
Between June 1963 and the end of 1965, it was established and hard surfaced on 1st Avenue, extending west-southwest from US 84/US 341/SR 27 (Newcastle Street).