Preparata dedicated a great part of his scientific activity to high energy physics, giving fundamental contributions to the construction of the standard model, the new synthesis of the subnuclear interactions.
His analysis reveals the existence of a non-trivial ground state of QCD and constitutes an important step forward in our understanding of interacting quantum fields.
Preparata discovered that condensed matter systems, when both at sufficiently low temperatures and high densities will spontaneously develop new coherent solutions of quantum electrodynamics (QED).
The Italian Society of Bioinformatics (BITS) starts each year its Annual Conference with the "Preparata Lecture", delivered by a distinguished keynote speaker.
Over the years, the Society, thanks to the contribution of the Preparata Foundation, also delivered Travel Grants to young researchers for the participation to BITS Annual Conferences.