Golden Grove is a census-designated place (CDP) in Greenville County, South Carolina, United States.

The western edge of Golden Grove follows the Saluda River, which is the border with Anderson County.

The main road through Golden Grove is South Carolina Highway 20, which leads north 9 miles (14 km) to Greenville and south through Piedmont 16 miles (26 km) to Belton.

Interstate 185 passes through the northern part of Golden Grove, crossing SC 20 at Exit 10.

20.7% of all households were made up of individuals, and 7.2% had someone living alone who was 65 years of age or older.