[2] The county was named for Alexander Hamilton, the first Secretary of the Treasury in the new United States government.

Hamilton County is included in the Grand Island, NE Metropolitan Statistical Area.

In the Nebraska license plate system, Hamilton County is represented by the prefix 28 (it had the 28th-largest number of vehicles registered in the county when the license plate system was established in 1922).

[8] As of the 2000 United States Census,[21] there were 9,403 people, 3,503 households, and 2,676 families residing in the county.

In only one national election since 1916 has the county selected the Democratic Party candidate.