He played college football at Virginia Tech and was selected by the Washington Redskins in the fifth round of the 2018 NFL draft.

[2] A five-star recruit, Settle committed to play football for the Virginia Tech Hokies in January 2015, choosing them over programs such as Louisville and USC.

[3] Settle attended and played college football at Virginia Tech under head coaches Frank Beamer and Justin Fuente.

[6] As a redshirt freshman in 2016, Settle played in all 14 of Virginia Tech's games, recording 17 tackles (seven for loss), two quarterback hurries and one blocked kick.

[8] In 2017, as a redshirt sophomore, he played in 13 games, tallying 36 tackles (12.5 for loss), four sacks, one pass deflection, two quarterback hurries, and one blocked kick.