It flows east-northeast for several tenths of a mile before turning north and receiving an unnamed tributary from the right.

The creek then turns north for a few tenths of a mile, entering a much broader valley and receiving an unnamed tributary from the left.

It then turns northeast for a short distance and crosses Pennsylvania Route 61 before reaching its confluence with Shamokin Creek.

[2] The mouth of the creek is in the United States Geological Survey quadrangle of Shamokin.

[5] Lick Creek was entered into the Geographic Names Information System on August 2, 1979.