It was renamed to the current name on June 24, 2013, after a $35 million donation from Larry and Judy Tanenbaum.

[1] The institute conducts research into various forms of cancer (colon, breast, pancreatic, prostate, lung, etc.

The institute has 100,000 sq ft (9,300 m2) of space and is split between the main hospital and the Joseph and Wolf Lebovic Health Complex.

The Lunenfeld-Tanenbaum Research Institute is a world pioneer in the fields of Systems Biology, Diabetes, and Infectious Bowel Disease.

Researchers are supported by the Mount Sinai Hospital Foundation, donors and external funding sources including:[2]