Owned and operated by the University Health Network (UHN), Toronto Rehab provides patients with rehabilitation care, helping people rebuild their lives and achieve individualized goals following injury and disability.

In 1950, the Lodge was acquired by the Canadian Paraplegic Association (CPA), and through the 1950s it was the only independent rehab facility for spinal cord injury in the world.

[5] To meet the demand for higher patient capacity, in 1974 work began on Lyndhurst Hospital in Toronto's Leaside neighbourhood.

[8] In 2008, work began on a $112 million expansion and renovation of the University Centre site, including construction of a 13-story tower with expanded research and educational space.

[12] In 2011, Toronto Rehab opened the iDAPT Centre Rehabilitation Research, where technologies and treatments to enhance the lives of people who are aging, ill or injured are tested in simulated environments.

[15] Under this rebranding, the research institute broadened its focus from rehabilitation to assisting people living with the effects of illness, aging, and disability.