The game included Web Gems instant replays, K-Zone pitching, Slam Zone hitting, and baserunner mode.
In 2005, in response to EA Sports' exclusive license with the National Football League and ESPN prohibiting any NFL 2K games for the foreseeable future, Take-Two Interactive signed an exclusive third-party licensing contract with Major League Baseball (MLB), MLBPA, and MLBAM to produce MLB games.
The agreement, which runs from Spring 2006 to 2012, allows for the console manufacturers Sony, Microsoft, and Nintendo to produce MLB titles for their respective platforms, but bars third party developers such as EA Sports from continuing or developing their own MLB games.
The 2006 edition, Major League Baseball 2K6, had the ESPN presentation and trademarks removed but the commentary team of Jon Miller and Joe Morgan remained intact.
The game included Inside Edge scouting, Swing Stick hitting, and Payoff Pitching.
The 2009 edition, Major League Baseball 2K9, represented the final act of a planned three-year development cycle that started with 2K7.
The game was slightly criticized for a copy and paste with a roster update but MLB 2K12 did improve on graphics.
Featured on the 2K13 cover is David Price of the Tampa Bay Rays replacing Justin Verlander.
[2] In May 2013, Nexon launched an online spinoff version of MLB 2K named Pro Baseball 2K (Korean: 프로야구 2K) exclusively in South Korea, however the game's servers were shut down in 2014, making it unplayable.