[2] There are two main modes: story and multiplayer, where the players can fight against other teams controlled by the game's artificial intelligence.

[2] The original story is based on the Dark Reign storyline and was written by Frank Tieri and Alex Irvine.

[10] Irvine also wrote other player versus environment events of the game, such as “Webbed Wonder,” where Spider-Man teams up with Howard the Duck to find out Aunt May's whereabouts.

[11] The game features an array of classic Marvel heroes and villains, including Spider-Man, Captain America, Wolverine, Iron Man, Thor, Black Widow, Storm and Magneto, along with lesser-known characters like Moonstone.

[15] Kamala Khan, who was announced as a new Marvel character in November 2013 and is the first Muslim superhero to lead a comic book series, was featured in the game.

Suit), wearing a suit mimicking Loki's powers from a dead mercenary;[23] Omega Red (Horseman of Pestilence), who was recruited by Apocalypse to join his Horsemen;[24][25] and Vulture (Armor Wars), wearing an armor built by Justin Hammer from reverse-engineered Stark tech.

[28] Puzzle Quest: Challenge of the Warlords was picked up by D3 Publisher and released on March 20, 2007, for the Nintendo DS and PlayStation Portable.

[28] It was an instant success, winning a 2008 Academy of Interactive Arts & Sciences award for Downloadable Game of the Year.

D3 Publisher stated that the revised title signified the beginning of the game's expansion beyond the "Dark Reign" storyline.

[9] On February 18, 2015, Sega Networks acquired Demiurge Studios, but the acquisition did not include the rights to Marvel Puzzle Quest.

[32][33] In early June 2022, it was announced that live operations of Marvel Puzzle Quest had been passed over to Broken Circle Studios, who had at that point been working on the game for several months.