The hospital charged five dollars a week for a private room and whatever the patient could afford in the public wards.
As the hospital made advancements in care, in 1952, MVH opened the Radioisotope Laboratory, a forerunner to nuclear medicine.
MVH was the first non-university hospital in Ohio to be authorized by the Atomic Energy Commission to use radioactive materials in research and patient care.
In 1983, MVH's first air ambulance, CareFlight, was put into service, which made rapid emergency transport available within a 75-mile (121 km) radius.
[13] In addition, Miami Valley Hospital completed a 484,000-square-foot (45,000 m2), 12-story tower, focusing on cardiac and orthopedic care.
[14] On June 2, 2022, a shooting occurred at the hospital, when Brian Booth, a 30-year-old inmate at the county jail, fatally shot Darrell Holderman, a 78-year-old security guard.