He also earned honorable mention Pac-10 All-Academic (2008–10), and the Brick Muller Award as Cal's Most Valuable Offensive Lineman (2009–11), for three seasons each.

[2][3] Schwartz was born in Pacific Palisades, California and grew up in West Los Angeles.

[4][5] He is the son of Lee Schwartz, a business consultant to manufacturing companies, and Olivia Goodkin, an attorney.

[4] When he started the ninth grade, he was already 6 feet 5 inches (1.96 m) tall and 240 pounds (110 kg), too big for the size restrictions of the local Pop Warner youth leagues.

His father, speaking of the fact that he has two sons playing in the National Football League, said: "I just kvell.

[4] Schwartz was a two-time All-State "underclassman" pick, and earned 2005 All-Western League and All-City honors as a junior.

[4][17] Academically, he had a 4.3 GPA and a 34 ACT, and was named to the Principal's Honor Roll and Dean's List.

[1][15] Coming out of high school, he received football offers from Cal, Michigan, Stanford, Virginia, Tennessee, Oregon, and Washington State.

[17] At a spring LA Scout.com combine, Schwartz measured 6 feet 5.5 inches (1.969 m) tall, and weighed 303 pounds (137 kg).

He graduated with a bachelor's degree in American Studies, with an emphasis on human development and identity.

[21] In 2010, he started all 12 games at left tackle, heading an offensive line that blocked for 1,167-yard rusher Shane Vereen.

[1] Schwartz was a member of the Jewish Sports Review's 2010 College Football All-America Team, received Cal's Brick Muller Award as its Most Valuable Offensive Lineman for the second straight year, and won Cal's Andy Smith Award as its player with the most Big "C" time.

[1][25] At the 2012 Senior Bowl, he started at right tackle for the winning North team, and had what was viewed as an impressive showing.

[40] Schwartz was named to the Pro Football Focus (PFF) 2012 All-Rookie Team, lauded for his "top-notch pass blocking".

[40] He and the Browns faced his brother's team, the Chiefs, at Arrowhead Stadium in Kansas City on October 27, 2013, and the two became the first Jewish siblings to play against each other in NFL history.

[45] In 2015, Schwartz started all 16 games for the Browns for the fourth consecutive season, playing all offensive snaps.

[47] Since Schwartz was selected, in his four years with the Browns, he started every single game at right tackle, without missing one offensive snap.

[44] On March 9, 2016, Schwartz signed a five-year, $33 million contract with the Kansas City Chiefs, making him one of the highest-paid right tackles in the NFL.

[51] Pro Football Focus graded him at 83.8, and gave him the Bruce Matthews Award as the NFL's top offensive lineman.

[54] On June 12, 2019, Schwartz signed a one-year contract extension with the Chiefs through the 2021 season for $11.255 million, making him the second-highest paid right tackle in the NFL.

[55] He was named to the Associated Press All-Pro Second-team, and to the 2019 Pro Football Writers of America All-AFC Team.

[59][62] During practice prior to the Chiefs' Week 6 game against the Buffalo Bills, Schwartz injured his back.