[2] In the Nebraska license plate system, Nance County is represented by the prefix 58 (it had the fifty-eighth-largest number of vehicles registered in the county when the license plate system was established in 1922).

The land that comprises Nance County was originally part of the Pawnee Reservation, created in 1857 when the Pawnee Indians signed a treaty with the United States ceding its lands in exchange for the reservation.

[4] In the mid-1870s the remainder of the reservation was sold, and in 1876 the tribe was relocated to its present-day location in central Oklahoma.

[7] Nearly all the land in Nance County was purchased by settlers or by investors for resale, instead of the homestead provisions common to most of Nebraska.

[3] The terrain of Nance County consists of rolling hills, sloping to the northeast.

In only one national election since 1936 has the county selected the Democratic Party candidate.