He played college football for the Michigan Wolverines and was selected by the Texans in the third round of the 2021 NFL draft.

[1][2] He attended Clay-Chalkville High School in Clay, Alabama, where he played wide receiver on the undefeated football team that won the 2014 Class 6A state championship.

[18] Heading into his first training camp, Collins was listed as a starting wide receiver alongside veterans Brandin Cooks and Chris Conley.

Again at the end of the NFL preseason, head coach David Culley named Collins a starting wide receiver, alongside Cooks and Conley.

[19] Collins made his first career start and NFL debut in the Texans' Week 1 victory against the Jacksonville Jaguars.

[20] Collins again started in the Texans' Week 2 loss to the Cleveland Browns, where he recorded one reception for 32 yards before exiting early in the first quarter with a shoulder injury.

[32] In a Week 4 win against the Pittsburgh Steelers, Collins set new single-game career highs with seven receptions for 168 receiving yards and two touchdowns.

[34] In a win-or-go-home scenario against the Colts in Week 18, Collins caught all nine of his targets for a career-high 195 yards and a career-long 75-yard touchdown in a 23–19 win, clinching the Texans a playoff spot for the first time since 2019.

[40][41] Collins led the league with 567 receiving yards before suffering a hamstring injury in Week 5 against the Buffalo Bills.