Northern Ireland competed at the 2022 Commonwealth Games in Birmingham, England between 28 July and 8 August 2022.

Lawn bowler Martin McHugh and boxer Michaela Walsh were the delegation's flagbearers during the opening ceremony.

[5][6] On 12 July 2022, CGNI declared that Leon Reid was barred from competing in the Games by BOCCG following a security risk assessment.

[13] JB Murphy and Lydia Boylan withdrew from the squad due to injury.

[18] By virtue of its position in the World Netball Rankings (as of 31 January 2022), Northern Ireland qualified for the tournament.

[14][15] A squad of three paratriathletes (plus one guide) was selected on 19 May 2022, all having qualified via the World Triathlon Para Rankings (as of 28 March 2022).