Saint Lucia competed at the 2022 Commonwealth Games at Birmingham, England from 28 July – 8 August 2022.

On July 23, 2022, a team of 13 athletes (ten men and three women) competing in four sports was named.

[2] Arthur Langelier and Julien Alfred were the country's flagbearers during the opening ceremony.

[4] By virtue of its status as the top Commonwealth Caribbean nation in the FIBA 3x3 Federation Rankings for women (on 1 November 2021), Saint Lucia was originally invited to play in the women's tournament.

[5][6] However, the basketball federation declined the invitation on account of not being able to send an adequately prepared squad to the Games.