[5][6][7] This gene encodes a member of the nucleoporin family.

The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC).

All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC.

Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

This article on a gene on human chromosome 12 is a stub.