Existing entirely within Butler County, SR 748 is not included within the National Highway System.

Bending to the north, the highway enters into rural Morgan Township.

The majority of SR 748 passes amid farmland, with the occasional patch of trees and numerous houses lining the roadway.

SR 748 next bends to the northeast and then east-northeast, as it crosses Morgan-Ross Road, and into Ross Township.

The highway passes a number of houses prior to arriving at its endpoint at a T-intersection with SR 129 approximately one-half mile (0.80 km) of U.S. Route 27 and the village of Millville.