The most common location of plica tissue is along the medial (inside) side of the knee.
If the plica tethers the patella to the femoral condyle, the symptoms may cause it to be mistaken for chondromalacia.
The plica themselves are remnants of the fetal stage of development where the knee is divided into three compartments.
Plica syndrome treatment focuses on decreasing inflammation of the synovial capsule.
Iontophoresis and phonophoresis have been utilized successfully against inflammation of the plica and synovial capsule.