The R63 is a tarred provincial route in South Africa that connects Calvinia with Komga via Carnarvon, Victoria West, Graaff-Reinet, Somerset East and King William's Town.

From Murraysburg, the R63 continues south-east for 89 kilometres as the Ouberg Pass to cross into the Eastern Cape and enter the city of Graaff-Reinet.

At this junction, the R63 turns eastwards and heads east-south-east for 98 kilometres, through Pearston (where it becomes the Bruintjieshoogte Pass), to the city of Somerset East, where it crosses the Little Fish River 3 times.

The R63 heads eastwards for another 21 kilometres to the town of Cookhouse, where it meets the N10 national route and crosses the Great Fish River.

From Adelaide, the R63 heads east-south-east for 31 kilometres to enter Fort Beaufort and meet the R67 road west of the town centre.

[1] From the R345 split near Alice, the R63 heads eastwards for 54 kilometres, through Middledrift and Dimbaza, to King William's Town in the Buffalo City Metropolitan Municipality, where it meets the N2 national route.