Reticuline is an alkaloid found in opium and a variety of plants including Lindera aggregata,[1] Annona squamosa,[2] and Ocotea fasciculata (also known as Ocotea duckei).

[3] Experiments in rodents suggest reticulije possesses potent central nervous system depressing effects.

[4] 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase uses S-adenosyl methionine and 3'-hydroxy-N-methyl-(S)-coclaurine to produce S-adenosylhomocysteine and (S)-reticuline.

Salutaridine can then be transformed progressively to thebaine, oripavine, and morphine.

The dictionary definition of reticuline at Wiktionary