Seattle Fish Guys has garnered a positive reception, especially for its poke, and is considered among the city's best seafood establishments.

[2][3] It has sold bivalves (including mussels),[4] clam chowder,[5] crab and shrimp cocktails, fish, poke,[6] and smoked lox.

[3][13][14] The restaurant's grand opening celebration was held on September 4,[15][16] and featured free samples and a mussel eating contest.

"[2] Aimee Rizzo of The Infatuation said of the poke in 2020, "Between the soy-marinated tuna, spicy salmon, furikake rice, and smoky macaroni salad, this is a bowl that's better than the sum of its parts—even though each part is excellent.

[5] Noms Magazine ranked the business eighth in a 2023 list of Seattle's thirteen best seafood restaurants, and recommended the crab sub, the idako (marinated baby octopus), and the poke bowl.