Seniko (Greek: Σενίκο) is a village and a community in the municipal unit of Selloi, Ioannina regional unit, Greece.

The community includes the villages Domolessa and Mikrochori.

It is built at 450 m above sea level, above the left bank of the river Tyria.

It is 2.5 km north of Agios Nikolaos, 6 km south of Chinka, 13 km west of Dodoni and 23 km southwest of Ioannina.