She became a drug dealer, which exposed her to situations that ultimately damaged her sanity; namely, being shot in the head by a police officer, and being put in Cloak's Darkforce, which awakened Shriek's latent mutant abilities.

They attracted the company of several other homicidal supervillains (Demogoblin, Doppelganger, and Carrion), and formed a "family," with Carnage and Shriek as the "parents" and the others as their "sons".

Shriek also used her mental powers to increase the chaos by causing a number of New Yorkers to violently turn on one another, although the heroes were able to calm the people down before they did anything too serious, such as killing their own children.

Carnage slew the Doppelganger and left the others to their defeat and capture, although he was subsequently contained by the Avengers after a clash with Spider-Man, Venom and Black Cat.

Shriek frees fellow inmates Gale, Webber, Pyromania, and Mayhem, and together they try to break out of the facility, opposed by Spider-Man and John Jameson.

Shriek and the other members of the jury deem Spider-Man guilty of ruining lives and creating supervillains, but before they can execute their sentence of death they are returned to their cells and have their memories altered by Traveller.

Shriek is brought to Hall Industries, where exposure to the Carnage symbiote, coupled with her witnessing guards beating Doppelganger (who had been attempting to rescue her) causes her to snap, and return to homicidal mania.

[11] Shriek regains consciousness, and is recruited by Caroline le Fay to battle the Fearless Defenders as a member of the new Doom Maidens.

The two killers flee pursued by Deadpool, who crashes their car with a combine harvester, severely injuring Shriek, and enraging Carnage.

[14] After being manipulated and abandoned by Boomerang, Shriek and three other members of the Sinister Sixteen sought revenge on him in the Bar With No Name, only to be defeated by him, Beetle, Overdrive, and Speed Demon.

[16] Detroit-based supervillain Nain Rouge afterward hires Shriek and a new Firebrand to be his enforcers, bringing them into conflict with the Great Lakes Avengers.

[17][18] Shriek later appears as a secret ally to Kraven the Hunter and the NYPD, who are hunting the Dinosaur People living beneath New York City.

They eventually return to Doverton and got the codexes – the symbiote remnants left on the bodies of previous hosts – from the citizens who were infected by Carnage.

In the present, after Kasady becomes Carnage, he breaks Barrison out of Ravencroft, and together they go on a rampage through San Francisco before capturing Mulligan and Anne Weying to lure out Venom.