[1] Thermotoga neapolitana was discovered in 1985 in Lucrino, Italy in a hotspring environment by Shimshon Belkin, Carl.

These galactomannans are associated with allowing an organism to endure harsh environments (through stabilization of the membrane), such as high temperatures.

[2] Glucose, sucrose, lactose, and starch nutrients all support growth when used as a sole source of energy.

Thermotoga neapolitana is unable to metabolize acetate, lactate, formate, pyruvate, propionate, mannitol, ethanol, methanol, glycerol, glutamate, or glycine.

[6] The hydrogen produced is considered extremely clean with a carbon monoxide level in the headspace of less than 50 parts per million.

[6] This may be promising from a bioengineering standpoint as hydrogen gas is commonly sought after as a possible alternative to fossil fuel burning for energy consumption.

[6] Though originally thought to be strictly anaerobic, Thermotoga neapolitana is more efficient in its catabolic pathways, especially its hydrogen production, when there are low levels of oxygen available (slightly above 10% total composition) in comparison to anoxic environments.

[4] Thermotoga neapolitana shows a DNA base composition of 41.3% Guanine + Cytosine(and therefore 58.7% Adenine + Thymine).

Most eukaryotes possess this gene, and it sometimes expressed to produce the rare osmolyte di-miyo-inositol 1,1' phosphate (DIP).