It is located to the north of Manila and has an approximate length of 27.1 kilometers (16.8 mi).

It starts at the La Mesa Reservoir in Quezon City and flows through Caloocan, Malabon, Valenzuela, and Navotas and empties into Manila Bay.

[1] In 2019, San Miguel Corporation pledged ₱1 billion for the cleanup of the Tullahan River as part of the Manila Bay rehabilitation effort.

[2] On June 15, 1995, the Metropolitan Manila Development Authority (MMDA) finished their clean-up of the Tullahan River.

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