The station, located in eastern Valence (Alixan), is about ten kilometres north-east from the town centre, allowing through trains to pass at full speed.

Built primarily of reinforced concrete, one of the main features is the glass on all walls of the station building.

The lower level, aligned roughly north-south, has 4 tracks: 2 in the centre allow through trains to pass without slowing, and 2 outer tracks are used for stopping TGV services.

The upper level, aligned north-east to south-west, has 2 platforms for trains on the Valence–Moirans railway, a classic line which runs southwest to Valence city, and northeast to Moirans and Grenoble.

Travel times have been decreased dramatically using Valence TGV station.