The 1998–99 UC Sampdoria season ended with the club's relegation to Serie B just eight years after winning the Serie A title in 1990–91.

Similarly to Napoli the year prior, the club was no longer a financial power when it came to signing players, while its high-profile signing, Ariel Ortega, did not deliver to the degree Sampdoria had hoped for.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Source: Worldfootball