In addition to the domestic league, SC Paderborn participated in this season's edition of the DFB-Pokal.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Win Draw Loss Fixtures Source: Soccerway Source: DFB The league fixtures were announced on 25 June 2021.