The 2021 Abu Dhabi Women's Tennis Open was a women's tennis tournament played on outdoor hard courts.

It was the inaugural professional edition of the tournament and a WTA 500 tournament on the 2021 WTA Tour.

It took place at the Zayed Sports City International Tennis Centre in Abu Dhabi, from 6 January to 13 January 2021.

Fourth-seeded Aryna Sabalenka won the singles title.

[1] The following players received entry using a protected ranking into the singles main draw: The following player received entry as an alternate: The following players received entry from the qualifying draw: The following players received entry as lucky losers: The following pairs received entry into the doubles main draw using a protected ranking: The following pairs received entry into the doubles main draw as alternates: