The 2021 Astana Open was a tennis tournament organized for professional tennis players, held in Astana, Kazakhstan, in 2021 on indoor hard courts.

It was primarily organized due to the cancellation of many tournaments during the 2021 ATP Tour and 2021 WTA Tour, because of the ongoing COVID-19 pandemic.

[1] It is the second edition of the tournament for the men and the first for the women.

This was Van Uytvanck's fifth singles title, and first of the year.

The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following pairs received wildcards into the doubles main draw: The following players received wildcards into the singles main draw: The following players received entry using protected rankings: The following players received entry from the qualifying draw: The following pairs received wildcards into the doubles main draw: