The 2021 Copa Colsanitas was a women's tennis tournament played on outdoor clay courts.

It was the 23rd edition of the tournament and part of the 250 category of the 2021 WTA Tour.

It took place at the Country Club in Bogotá, Colombia, from 5 April to 11 April 2021.

[1] *per team The following players received wildcards into the main draw: The following players received entry from the qualifying draw: The following pairs received wildcards into the doubles main draw: