Emma Raducanu defeated Leylah Fernandez in the final, 6–4, 6–3 to win the women's singles tennis title at the 2021 US Open.

[1][2][3] Aged 18, Raducanu was the youngest major champion since Maria Sharapova at the 2004 Wimbledon Championships, and with a ranking of world No.

Raducanu won the title on only her second major main-draw appearance, an Open Era record.

[9] The defeats of Karolína Plíšková and Barbora Krejčíková in the quarterfinals guaranteed two first-time major finalists; Raducanu and Fernandez emerged to become those players.

This marked the final US Open appearance of 2016 champion Angelique Kerber; she lost to Fernandez in the fourth round.

As a result of pandemic-related adjustments to the ranking system, players are defending the greater of their points from the 2019 and 2020 tournaments.