The 2021 Yarra Valley Classic was a tournament on the 2021 WTA Tour, one of six events in the 2021 Melbourne Summer Series.

Players who had originally intended to participate in this tournament or the Gippsland Trophy, but were forced to undergo strict quarantine measures upon arrival in Australia, were able to participate in the 2021 Grampians Trophy.

The entry list of 2021 Australian Open was used to determine the entry list of this tournament; with half the players (selected randomly) playing the Yarra Valley Classic, and the other half playing the 2021 Gippsland Trophy.

[1] In the women's singles final, Ashleigh Barty defeated Garbiñe Muguruza in straight sets, while Shuko Aoyama and Ena Shibahara won in women's doubles.

[2] The following players received wildcards into the main draw: The following players received entry using a protected ranking into the Australian Open singles main draw, and hence this tournament as well: The following players received entry from the Australian Open qualifying draw: The following players received entry into this tournament as they were potential lucky losers for the Australian Open singles main draw: The following players received entry as an alternate: The following pairs received a wildcard into the doubles main draw: The following pair received entry as alternates: *per team Other events in the 2021 Melbourne Summer Series:[3]