On the touchdown drive, Herbert converted a 4th and inches with a quarterback sneak, and Williams caught a 39-yard pass to the Chiefs' 1 yard line; Horvath scored two plays later.
A 3rd-down Nasir Adderley interception on the ensuing drive was nullified by an illegal contact penalty on Callahan, leading to Mahomes' first touchdown pass.
Houston kicker Kaʻimi Fairbairn missed a 46-yard field goal late in the opening quarter, and the Chargers scored again when Ekeler broke through the right guard area for his first touchdown of the season.
Helped by Tillery's second-down sack, the Charger defense allowed only a field goal, keeping Los Angeles ahead at 27–24 with 8:30 to play.
Palmer drew a 30-yard pass interference penalty on the game's first play, and Bandy converted a 4th and 2 with and 4-yard catch, but the Chargers were pushed back by a Calpp false start and had to punt.
A 21-yard pass interference call no Jackson then converted a Denver 3rd and 14; the Broncos reached a 3rd and 1 at the Los Angeles 29 before Mack sacked Russell Wilson and Brandon McManus kicked his first field goal.
Unnecessary roughness and pass interference penalties by Denver contributed 35 yards to the ensuing Chargers drive, which ended with Hopkins' third field goal with four minutes to play.
Both teams had one further possession in overtime: Tranquill again sacked Wilson on 3rd down to force a punt, and Herbert's pass from his own 44 fell incomplete as time expired.
Ekeler was then initially ruled to have avoided touching the ground while being tackled a yard behind the line of scrimmage; he ran clear for a touchdown that was overturned when replays showed his left elbow graze the turf.
As the Falcons had no timeouts left, Los Angeles could run the clock down and kick a field goal, but Ekeler had the ball knocked loose as he dove forward to the 20.
Herbert immediately found Palmer for 22 yards to move Los Angeles back into field goal range, and Dicker made the winning kick two plays later.
[146] Los Angeles became the third team in NFL history to trail by at least 10 points after the opening quarter of four consecutive games, following the Denver Broncos of 1962 and 1963, and the Tampa Bay Buccaneers of 1988.
[149] Herbert returned for the Los Angeles failed to score in the second half, picking up only three first downs in five possessions and advancing no further than the San Francisco 44.
After gaining 7 yards on three plays, Los Angeles turned the ball over on downs when Herbert was hit as he passed and Palmer couldn't pull in his wild throw.
[152] Los Angeles finished that drive with a field goal, and Kansas City responded with completions of 34 and 40 yards by Mahomes before Travis Kelce's first touchdown catch.
Mahomes threw incomplete on 3rd and 4 midway through the winning drive, but James was judged to have committed defensive holding, sparing the Chiefs a 4th-down conversion attempt.
[156] The teams exchanged field goal tries at the start of the second half, with Matt Prater wide left from 49 yards and Dicker successful from 26 to tie the game.
The Charger defense gave up two first downs on the next drive, but eventually forced a punt; Los Angeles took over on their own 9 with five minutes to play and a chance to tie the game.
On their first drive of the game Los Angeles went 78 yards in 15 plays, reaching a 4th and goal from the Miami 2 before Carter stumbled while taking Herbert's pass in the left flat and was tackled for no gain.
To that point, the Dolphins had gained only one first down on three possessions, but they responded to the Chargers' touchdown in unusual fashion; Gilman forced a fumble that was knocked out of a scrum of players on both sides trying to recover it.
Miami crossed midfield on each of their next possessions, but were pushed back both times; Fox sacked Tua Tagovailoa on the first drive, and Tranquill pressured him into committing intentional grounding on the second one.
Palmer then failed to gather an onside kick, but Niemann fell on the loose ball and recovered, denying the Dolphins an opportunity for a game-winning drive.
The Colts reached a 4th and 1 at the 12 and went for it on the first play of the final quarter, but the Los Angeles defensive line stopped Foles for no gain on a quarterback sneak.
After a Rams punt, Ekeler scored again; he ran through the right guard area, broke a single tackle near the line of scrimmage, then raced clear for a 72-yard touchdown.
[167] The Rams responded with their lone touchdown of the game, then an athletic one-handed catch by Williams set up Dicker's field goal late in the half for a 17–10 lead.
Dicker restored Los Angeles' seven-point lead with only 26 seconds left in the half, but that was enough time for Denver to level at 17–17; Jerry Jeudy got behind Gilman and James for a 57-yard catch from Russell Wilson, who threw a touchdown on the following play.
His first drive resulted in a punt, which was muffed by the Broncos and recovered by Gilman at the Denver 29; that led to Daniel's passes to Allen and Palmer for a touchdown and two-point conversion.
[176] On the second play of the game, Jags QB Trevor Lawrence's pass was intercepted by Drue Tranquill, who returned it 15 yards to the Jacksonville 18-yard line.
Ekeler then took the ball to the end zone with three consecutive carries, the last one a 6-yard touchdown run that gave the Chargers a 17–0 lead with 37 seconds left in the first quarter.
Jacksonville was quickly forced to punt and the Chargers drove back for more points, this time going 67 yards in 13 plays, including Herbert's 23-yard completion to tight end Gerald Everett to convert a 3rd and 11.