The 2022 Open du Pays d'Aix was a professional tennis tournament played on clay courts.

It was the ninth edition of the tournament which was part of the 2022 ATP Challenger Tour.

It took place in Aix-en-Provence, France between 2 and 8 May 2022.

The following players received wildcards into the singles main draw: The following players received entry into the singles main draw as alternates: The following players received entry from the qualifying draw: