The regiment is named for the city of Arezzo in Tuscany and part of the Italian Army's infantry arm.

In May 1939,the regiment joined the 53rd Infantry Division "Arezzo", which in June 1940 was transferred to occupied Albania.

[2] The 225th Infantry Regiment (Brigade "Arezzo") was formed during World War I on 18 May 1916 in Castelfranco Veneto near the Italian Front.

The regiment consisted of three battalions, which each fielded four fusilier companies and one machine gun section.

In May and June 1917 the brigade fought in the Tenth Battle of the Isonzo initially at Monfalcone and Duino and then on the slopes of Flondar and Monte Ermada.

[5][6][8] At the outbreak of World War II the regiment consisted of a command, a command company, three fusilier battalions, a support weapons battery equipped with 65/17 infantry support guns, and a mortar company equipped with 81mm Mod.

For its conduct during the war the 225th Infantry Regiment "Arezzo" was awarded a Silver Medal of Military Valor.

[2][5] After the war the Arezzo division moved to Korçë in Albania, where it performed anti-partisan duties until September 1943.

However a large number of the division's troops escaped and joined partisans operating in the area.