In 1964 the regiment was reorganized and moved to Tarcento, where it was tasked with maintaining and manning fortifications of the Alpine Wall on the border with Yugoslavia.

On the same date the depot in Cuneo formed the 1st Regiment Cacciatori delle Alpi, whose commanding officer was Enrico Cosenz.

Also on the same date a depot was formed in Acqui, which was tasked with training volunteers arriving from the Grand Duchy of Tuscany and the central Italian Papal Legations.

On 7 April 1859, the depot in Savigliano formed the 2nd Regiment Cacciatori delle Alpi, whose commanding officer was Giacomo Medici.

[2][4] At the outbreak of the war on 26 April the Cacciatori delle Alpi Corps consisted of two regiments and a Horse Guides Squadron.

On 22 May the corps reached Arona and in the following night, two companies crossed the Ticino river and occupied Sesto Calende in Lombardy.

[2] On 27 Mary 1859, Garibaldi began his march to Como and quickly encountered Austrian forces, which led to the Battle of San Fermo.

On 2 June 1859, the Regiment Cacciatori degli Appennini was assigned to the Garibaldi's corps and on the same day French forces commenced the crossing of the Ticino river into Lombardy.

On 8 July 1859, the 4th Regiment Cacciatori delle Alpi arrived in Sondrio, where it joined the rest of Garibaldi's corps.

[2] After the armistice Garibaldi reorganized his forces and by then the Cacciatori delle Alpi Corps consisted of the following units:[2] On 15 July 1859, with peace negotiations with Austria underway, the Cacciatori delle Alpi ceased recruiting, and on 20 July the first troops were released from their regiments.

On 7 August 1859, Garibaldi resigned as commander of the corps and left with the Horse Guides Squadron to occupy Bologna.

At the same time Giuseppe Garibaldi, led the Expedition of the Thousand to Sicily, whose troops were primarily veterans of the Cacciatori delle Alpi Corps.

[2] On 15 June 1859, the corps' Horse Guides Squadron was awarded a Bronze Medal of Military Valor for its conduct during the war.

On the same date the corps' medical units were awarded a shared Bronze Medals of Military Valor for the care they had provided to friendly and enemy injured personnel.

From 1862 to 1863 the Brigade of the Alps operated in the area between Trapani, Castellammare del Golfo, and Palermo to suppress the anti-Sardinian revolt, which had erupted in Southern Italy after the annexation of the Kingdom of the Two Sicilies.

At the time the 52nd Infantry Regiment consisted of the II, III, and IV battalions, each of which fielded four fusilier companies and one machine gun section.

On 19 July, the regiment's IV Battalion reached the first Austro-Hungarian trenches, but was forced to retreat after the enemy launched a counterattack.

In November 1915, the Brigade "Calabria" tried again to conquer the summit of the Col di Lana, and the 52nd Infantry Regiment attacked towards Varda and Cherz.

On 7 November 1917, the Brigade "Alpi" entered the front between the bridge over the Piave river at Vidor and Grave di Ciano.

In August 1918, the brigade participated in the Hundred Days Offensive, initially in September along the Aisne river at Vauxcéré, and then from 11 October at Chemin des Dames.

In 1935-36 the 52nd Infantry Regiment "Alpi" provided 15 officers and 123 troops to units deployed to East Africa for the Second Italo-Ethiopian War.

On 10 June 1940, Italy entered World War II by invading France and the "Cacciatori delle Alpi" division was part of the 1st Army's reserve.

[2][7][9] In January 1941, the 22nd Infantry Division "Cacciatori delle Alpi" was transferred to Albania to shore up the crumbling Italian front during the Greco-Italian War.

On 21 January, the division entered the front between Qafë and Bubës, with the task to block Greek attacks in the Osum river valley.

On 9–10 February 1941, a minor defensive battle was won by the Italians at Mali i Firtit, which stopped the Greek advance.

On 15 April 1941, the Italian spring offensive commenced and the "Cacciatori delle Alpi" division attacked at Korçë, reaching Cerovë after some fighting.

On 21 April 1941, the division crossed the Vjosa river near Përmet and blocked the retreat route of the Greek army.

[2][9] In July 1941, the "Cacciatori delle Alpi" division was transferred to Podgorica in Montenegro on occupation duty.

[13] On 8 September 1943, the Armistice of Cassibile was announced and the "Cacciatori delle Alpi" division, which at the time was on occupation duty in the Ljubljana and Rijeka area in Slovenia, was disbanded by invading German forces.

[2][7][9] On 1 July 1958, the 52nd Infantry Regiment "Alpi" was reformed by renaming the existing 2nd Recruits Training Center in Cuneo.