2UXW, 3B963711370ENSG00000072778ENSMUSG00000018574P49748P50544NM_000018NM_001033859NM_001270447NM_001270448NM_017366NP_000009NP_001029031NP_001257376NP_001257377NP_059062Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) is an enzyme that in humans is encoded by the ACADVL gene.

[10] ACADVL is linked with very long-chain acyl-coenzyme A dehydrogenase deficiency (VLCADD), which has many symptoms, and typically presents as one of three phenotypes.

The first is severe, with an early childhood onset and high mortality rate; the most common symptom is this form is cardiomyopathy.

The deficiency is treated systematically, but certain conditions such as fasting, myocardial irritation, dehydration, and high fat diets are avoided in an attempt to prevent secondary complications.

[13] This article incorporates text from the United States National Library of Medicine, which is in the public domain.