An adenosine receptor antagonist is a drug which acts as an antagonist of one or more of the adenosine receptors.
[1] The best known are xanthines and their derivatives (natural: caffeine,[2] theophylline,[3] and theobromine; and synthetic: PSB-1901[4]), but there are also non-xanthine representatives (e.g. ISAM-140,[5] ISAM-R316,[6] etrumadenant,[7] and AZD-4635[8])
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