[1][2] Catalytic hydrogenation can be used to reduce amides to amines; however, the process often requires high hydrogenation pressures and reaction temperatures to be effective (i.e. often requiring pressures above 197 atm and temperatures exceeding 200 °C).
[11] Iron catalysis by triiron dodecacarbonyl in combination with polymethylhydrosiloxane has been reported.
[12] Lawesson's reagent converts amides to thioamides, which then catalytically desulfurize.
Lithium aluminum hydride reduces an excess of N,N-disubstituted amides to an aldehyde:[citation needed] With further reduction the alcohol is obtained.
Schwartz's reagent reduces amides to aldehydes,[14] and so does hydrosilylation with a suitable catalyst.