Anguilla competed at the 2022 Commonwealth Games in Birmingham, England between 28 July and 8 August 2022.

[1] The team participated in the Games for the seventh time.

Anguilla's team consisted of 13 athletes (12 men and one woman) competing in four sports.

[3] The following is the list of number of competitors participating at the Games per sport/discipline.

[4] Anguilla entered one male swimmer, marking the country's debut in the sport at the Commonwealth Games.