2D4678512298ENSG00000182389ENSMUSG00000017412O00305Q8R0S4NM_001330113NM_001330114NM_001330115NM_001330116NM_001330117NM_001330118NM_001355059NP_001317042NP_001317043NP_001317044NP_001317045NP_001317046NP_001317047NP_001341988Voltage-dependent L-type calcium channel subunit beta-4 is a protein that in humans is encoded by the CACNB4 gene.

[5][6] This gene encodes a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex.

Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing.

The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation.

[7][8] This article incorporates text from the United States National Library of Medicine, which is in the public domain.