[2][3] Other calcium channels can also be regulated by both voltage and ligands to provide precise control over ion flow.
The following tables explain gating, gene, location and function of different types of calcium channels, both voltage and ligand-gated.
Cat-Sper channels, found in mammalian sperm, are one example of this as they are voltage gated and ligand regulated.
In most areas of the body, depolarization is mediated by sodium influx into a cell; changing the calcium permeability has little effect on action potentials.
L-type calcium channel blockers selectively inhibit these action potentials in smooth muscle which leads to dilation of blood vessels; this in turn corrects hypertension.