Carboxylation

In chemistry, the term carbonation is sometimes used synonymously with carboxylation, especially when applied to the reaction of carbanionic reagents with CO2.

[9] Carbon-based life originates from carboxylation that couples atmospheric carbon dioxide to a sugar.

Ribulose-1,5-bisphosphate carboxylase/oxygenase, the enzyme that catalyzes this carboxylation, is possibly the single most abundant protein on Earth.

[14] GGCX requires vitamin K as a cofactor and performs the reaction in a processive manner.

[16] For example, in prothrombin, calcium binding allows the protein to associate with the plasma membrane in platelets, bringing it into close proximity with the proteins that cleave prothrombin to active thrombin after injury.