Dilazep

Dilazep is a vasodilator that acts as an adenosine reuptake inhibitor.

[1][2] It is used for the treatment of cardiopathy and renal disorders.

[3] The reaction of bis-(3-hydroxypropyl)-ethylene diamine (1) with 1-Bromo-3-chloropropane (2) gives homopiperazine [19970-80-0] (3).

Esterification by reaction with 3,4,5-Trimethoxybenzoyl Chloride [4521-61-3] (4) completed the synthesis of Dilazep (5).

This drug article relating to the cardiovascular system is a stub.

Thieme Patent: [ 4 ] Prec (page 935): [ 5 ]