Flavodoxin fold

The flavodoxin fold is a common α/β protein fold, second only to the TIM barrel fold.

It has three layers, with two α-helical layers sandwiching a 5-stranded parallel β-sheet.

The order of strands within the sheet is 2-1-3-4-5.

This motif is present for example in lactate dehydrogenase (PDB: 1A5Z​) or phosphoglycerate kinase (PDB: 1FW8​).

[1] This protein-related article is a stub.

Ribbon diagram of CheY (a regulator of the chemotactic response in bacteria, PDB accession code 3CHY), which adopts the flavodoxin fold. Ribbon is colored from blue (N-terminus) to red (C-terminus).