It is the highest oxide of hassium, a transactinide transition metal.

It has little use outside of scientific interest, where it is often studied in comparison to osmium tetroxide and ruthenium tetroxide, its lighter octavalent group 8 element analogs.

Because of the extreme cost and difficulty of producing hassium, hassium tetroxide has never been obtained in macroscopic amounts, as only a few molecules have ever been synthesized.

As a result, many of its physical properties are experimentally uncharacterized and unknown.

[3][2] Hassium tetroxide can be combined with sodium hydroxide in an acid-base reaction, in which case it acts like the acid, to form sodium hassate(VIII):[5]