The 2007–08 Israeli Premier League season began on 18 August 2007 and ended on 1 June 2008, with Beitar Jerusalem win their second consecutive title.
Two teams from Liga Leumit were promoted at the end of the previous season: Ironi Kiryat Shmona and Bnei Sakhnin.
The two teams relegated were Hakoah Amidar Ramat Gan and Hapoel Petah Tikva.
Bnei Sakhnin returned after an absence of one season, while Ironi Kiryat Shmona made their debut in the top flight.
Hakoah Amidar Ramat Gan and Hapoel Petah Tikva were relegated after finishing in the bottom two places in the 2006-07 season.