Since the release of her debut fragrance Glow in 2001, the line expanded to include clothing, watches, accessories, bedding and perfume, becoming a huge success in the United States and international markets.

The line, which would eventually also include eyewear, swimwear, accessories and a fragrance, was to be backed up by an investment group led by Andy Hilfiger and Larry Stemerman.

"[3] Lopez officially announced and launched a lifestyle brand as "J.Lo by Jennifer Lopez" in April 2001; she introduced it as not only a fashion line, but as something that would also include many different types of clothing for young and older women, including swimwear, fragrances, eyewear, jewelry, hats, gloves, and scarves, outerwear, handbags, lingerie, bed sheets, decorative pillows, watches and footwear.

[11] In 2003, Lopez signed a deal with the Warnaco Group to manufacture and sell a new lingerie collection including underwear, lounge-wear and sleepwear; Joe Gromek, the president and chief executive officer of the Warnaco Group stated ""Jennifer's femininity and signature style have made her a fashion icon and we are confident that JLO Lingerie will bring some new excitement to intimate apparel.

It was inspired by Lopez's fashion and made into sporting clothes such as key pieces novelty tops, shorts, skirts and bottoms, denim sportswear jackets and jeans.

[14] On the partnership, a Lancaster representative said "The products will be designed to reflect the inspirational, confident and desirable qualities of Jennifer Lopez herself.

A year after the line's official launch by 2003, Lopez had already sold $175M worth of products in the U.S.[12] Jeffrey Peterson, Quepasa Chairman and Founder said "In a similar way to how Quepasa pioneered the Hispanic Internet on a national level in the United States during the late '90s, Jennifer Lopez started the trend of celebrity fashion brands in 2001.

[24] At the Los Angeles premiere of Monster-in-Law, more than 100 protesters from People for the Ethical Treatment of Animals (PETA) held a demonstration to highlight their concerns.